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FGF19 抗体 (AA 25-216) (PE)

The 兔 多克隆 anti-FGF19 antibody is suitable to detect FGF19 in samples from 人. It has been validated for FACS.
产品编号 ABIN7990474
发货至: 中国
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Room 801-803
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Quick Overview for FGF19 抗体 (AA 25-216) (PE) (ABIN7990474)

抗原

See all FGF19 抗体
FGF19 (Fibroblast Growth Factor 19 (FGF19))

适用

  • 71
  • 5
  • 4
  • 3

宿主

  • 58
  • 12
  • 5
  • 1

克隆类型

  • 54
  • 17
  • 3
多克隆

标记

  • 40
  • 6
  • 5
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This FGF19 antibody is conjugated to PE

应用范围

  • 43
  • 28
  • 21
  • 20
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 12
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-216

    原理

    Anti-FGF19 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human FGF19 recombinant protein (Position: L25-K216).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    FGF19 (Fibroblast Growth Factor 19 (FGF19))

    别名

    FGF19

    背景

    Background: FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity. FGF19 is the orthologous protein in humans. They are often referred together as FGF15/19.

    Gene Full Name: fibroblast growth factor 19

    基因ID

    9965

    UniProt

    O95750

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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