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FASL 抗体 (Middle Region) (FITC)

The FITC-conjugated 兔 多克隆 anti-FASL antibody (ABIN7989722) specifically detects FASL in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7989722
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for FASL 抗体 (Middle Region) (FITC) (ABIN7989722)

抗原

See all FASL 抗体
FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

适用

  • 132
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宿主

  • 86
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克隆类型

  • 93
  • 60
多克隆

标记

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This FASL antibody is conjugated to FITC

应用范围

  • 80
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Flow Cytometry (FACS)
  • 抗原表位

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    Middle Region

    原理

    Anti-FASL/FASLG Antibody FITC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human FASL/FASLG, which shares 85% and 80% amino acid (aa) sequence identity with mouse and rat FASL/FASLG, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

    别名

    FASLG

    背景

    Background: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

    Gene Full Name: Fas ligand

    基因ID

    356

    UniProt

    P48023

    途径

    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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