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FADD 抗体 (C-Term) (APC)

The 兔 多克隆 anti-FADD antibody is suitable to detect FADD in samples from 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7989691
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FADD 抗体 (C-Term) (APC) (ABIN7989691)

抗原

See all FADD 抗体
FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

适用

  • 112
  • 98
  • 54
  • 19
  • 15
小鼠, 大鼠

宿主

  • 147
  • 17

克隆类型

  • 121
  • 43
多克隆

标记

  • 77
  • 11
  • 6
  • 6
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  • 4
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  • 3
  • 3
  • 3
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This FADD antibody is conjugated to APC

应用范围

  • 122
  • 62
  • 54
  • 48
  • 20
  • 15
  • 15
  • 15
  • 11
  • 7
  • 5
  • 3
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 41
    • 17
    • 17
    • 15
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-FADD Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse FADD, which shares 63.6% and 81.8% amino acid (aa) sequence identity with human and rat FADD, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

    别名

    Fadd

    背景

    Background: FADD, Fas-Associated protein with Death Domain, is a universal adaptor protein in apoptosis that mediates signaling of all known death domain-containing members of the TNF receptor superfamily. The FADD gene contains 2 exons and spans approximately 3.6 kb. By analysis of somatic cell hybrid panels and by fluorescence in situ hybridization, the FADD gene is mapped to 11q13.3. The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, thus, it participates in the death signaling initiated by these receptors.

    Gene Full Name: Fas associated via death domain

    基因ID

    14082

    UniProt

    Q61160

    途径

    Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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