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EPH Receptor A3 抗体 (AA 59-514) (HRP)

This 兔 多克隆 antibody specifically detects EPH Receptor A3 in WB, ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7987968
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for EPH Receptor A3 抗体 (AA 59-514) (HRP) (ABIN7987968)

抗原

See all EPH Receptor A3 (EPHA3) 抗体
EPH Receptor A3 (EPHA3)

适用

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宿主

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克隆类型

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多克隆

标记

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This EPH Receptor A3 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 59-514

    原理

    Anti-Eph receptor A3/EPHA3 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Eph receptor A3/EPHA3 recombinant protein (Position: D59-A514).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    EPH Receptor A3 (EPHA3)

    别名

    EPHA3

    背景

    Background: Ephrin Receptor EphA3, is also known as human embryo kinase(HEK) or Eph-like tyrosine kinase1(ETK1). Kinases that phosphorylate proteins on tyrosine residues(protein tyrosine kinases, PTKs), such as EPHA3, form a structurally related group of molecules that exhibit functional diversity. Genetic alterations that lead to the inappropriate activation or expression of PTKs may be oncogenic. Many growth factor receptors are PTKs, e.g., the receptors for epidermal growth factor(EGFR), platelet-derived growth factor(PDGFR1,PDGFR2), colony-stimulating factor-1(CSF1R), and stem cell growth factor. The EPHA3 gene is mapped to 3p11.2. Sequence comparison with other PTKs showed a high degree of homology with members of the EPH and ELK(EPHB1) families of receptor tyrosine kinases. Within axial nerves, establishment of discrete afferent and efferent pathways depends on coordinate signaling between coextending sensory and motor projections.

    Gene Full Name: EPH receptor A3

    基因ID

    2042

    UniProt

    P29320

    途径

    RTK signaling, Regulation of Cell Size
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