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p300 抗体 (Middle Region) (Fluoro594)

The Fluoro594-conjugated 兔 多克隆 anti-p300 antibody (ABIN7986749) specifically detects p300 in FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7986749
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for p300 抗体 (Middle Region) (Fluoro594) (ABIN7986749)

抗原

See all p300 (EP300) 抗体
p300 (EP300) (E1A Binding Protein P300 (EP300))

适用

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人, 小鼠

宿主

  • 118
  • 10

克隆类型

  • 116
  • 12
多克隆

标记

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This p300 antibody is conjugated to Fluoro594

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

    • 36
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    Middle Region

    原理

    Anti-KAT3B/p300/EP300 Antibody Fluoro594 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human KAT3B/p300/EP300, which shares 76.5% amino acid (aa) sequence identity with mouse EP300.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    p300 (EP300) (E1A Binding Protein P300 (EP300))

    别名

    EP300

    背景

    Background: E1A binding protein p300 also known as EP300 or p300 is a protein that in humans is encoded by the EP300 gene. The EP300 gene is located on the long (q) arm of the human chromosome 22 at position 13.2. This protein regulates the activity of many genes in tissues throughout the body. It plays an essential role in regulating cell growth and division, prompting cells to mature and assume specialized functions (differentiate), and preventing the growth of cancerous tumors. The EP300 protein appears to be critical for normal development before and after birth. It carries out its function by activating transcription. In addition, the protein functions as histone acetyltransferase that regulates transcription via chromatin remodeling, and is important in the processes of cell proliferation and differentiation. EP300 also mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein.

    Gene Full Name: EP300 lysine acetyltransferase

    基因ID

    2033

    UniProt

    Q09472

    途径

    p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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