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Dual Specificity Phosphatase 3 (DUSP3) (C-Term) 抗体 (Fluoro647)

This 兔 多克隆 antibody specifically detects Dual Specificity Phosphatase 3 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7986486
发货至: 中国
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Quick Overview for Dual Specificity Phosphatase 3 (DUSP3) (C-Term) 抗体 (Fluoro647) (ABIN7986486)

抗原

See all Dual Specificity Phosphatase 3 (DUSP3) 抗体
Dual Specificity Phosphatase 3 (DUSP3)

适用

  • 68
  • 45
  • 28
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 74
  • 9

克隆类型

  • 74
  • 9
多克隆

标记

  • 32
  • 8
  • 6
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Fluoro647

应用范围

  • 49
  • 29
  • 21
  • 18
  • 13
  • 13
  • 12
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 20
    • 15
    • 12
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    C-Term

    原理

    Anti-DUSP3 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human DUSP3, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Dual Specificity Phosphatase 3 (DUSP3)

    别名

    DUSP3

    物质类

    Viral Protein

    背景

    Background: DUSP3 (Dual-specificity phosphatase 3), also called VHR, is a member of the dual specificity protein phosphatase subfamily. DUSPs constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP3 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs. The DUSP3 gene is mapped on 17q21.31. Confocal microscopy demonstrated that phosphorylated VHR accumulated at the immune synapse between the T cell and the antigen-presenting cell in the presence of antigen. Tyrosine phosphorylation of VHR affects protein-protein interaction, subcellular location, or substrate targeting, given that tyr138 is located on the opposite side of the VHR catalytic center.

    Gene Full Name: dual specificity phosphatase 3

    Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

    基因ID

    1845

    UniProt

    P51452

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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