DDX58 抗体 (AA 203-925) (PE)
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Quick Overview for DDX58 抗体 (AA 203-925) (PE) (ABIN7984282)
抗原
See all DDX58 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 203-925
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原理
- Anti-DDX58/RIG-1 Antibody PE Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human RIGI shares 78.2% amino acid (aa) sequence identity with mouse RIGI.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DDX58/RIG-1 recombinant protein (Position: K203-K925). Human RIGI shares 78.2% amino acid (aa) sequence identity with mouse RIGI.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))
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别名
- RIGI
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背景
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Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
Gene Full Name: RNA sensor RIG-I
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基因ID
- 23586
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UniProt
- O95786
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途径
- Activation of Innate immune Response, Hepatitis C
抗原
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