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DDX58 抗体 (AA 203-925) (Fluoro488)

The 兔 多克隆 anti-DDX58 antibody is suitable to detect DDX58 in samples from 人. It has been validated for FACS.
产品编号 ABIN7984276
发货至: 中国
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Quick Overview for DDX58 抗体 (AA 203-925) (Fluoro488) (ABIN7984276)

抗原

See all DDX58 抗体
DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

适用

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宿主

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克隆类型

  • 94
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多克隆

标记

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This DDX58 antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 203-925

    原理

    Anti-DDX58/RIG-1 Antibody Fluoro488 Conjugated

    交叉反应 (详细)

    No cross reactivity with other proteins.

    预测反应

    Human RIGI shares 78.2% amino acid (aa) sequence identity with mouse RIGI.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DDX58/RIG-1 recombinant protein (Position: K203-K925). Human RIGI shares 78.2% amino acid (aa) sequence identity with mouse RIGI.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

    别名

    RIGI

    背景

    Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.

    Gene Full Name: RNA sensor RIG-I

    基因ID

    23586

    UniProt

    O95786

    途径

    Activation of Innate immune Response, Hepatitis C
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