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DDX58 抗体 (AA 871-925) (Cy3)

The 兔 多克隆 anti-DDX58 antibody is suitable to detect DDX58 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7984264
发货至: 中国
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Quick Overview for DDX58 抗体 (AA 871-925) (Cy3) (ABIN7984264)

抗原

See all DDX58 抗体
DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

适用

  • 110
  • 52
  • 28
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 104
  • 9
  • 1

克隆类型

  • 94
  • 20
多克隆

标记

  • 47
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This DDX58 antibody is conjugated to Cy3

应用范围

  • 85
  • 29
  • 23
  • 22
  • 19
  • 14
  • 14
  • 11
  • 8
  • 6
  • 4
  • 3
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 13
    • 11
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 871-925

    原理

    Anti-DDX58 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    coli-derived human DDX58 recombinant protein (Position: H871-K925). Human DDX58 shares 83.3% amino acid (aa) sequence identity with mouse DDX58.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human DDX58 recombinant protein (Position: H871-K925). Human DDX58 shares 83.3% amino acid (aa) sequence identity with mouse DDX58.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

    别名

    DDX58

    背景

    Background: RIG-I (retinoic acid-inducible gene I) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded (in humans) by the DDX58 gene. RIG-I is part of the RIG-I-like receptor family, which also includes MDA5 and LGP2, and functions as a pattern recognition receptor that is a sensor for viruses such as influenza A, Sendai virus, and flavivirus. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.

    Gene Full Name: RNA sensor RIG-I

    基因ID

    23586

    UniProt

    O95786

    途径

    Activation of Innate immune Response, Hepatitis C
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