COX1 抗体 (N-Term) (Fluoro488)
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北京 101111
Quick Overview for COX1 抗体 (N-Term) (Fluoro488) (ABIN7982860)
抗原
See all COX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-MTCO1/MT-CO1 Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MTCO1.
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亚型
- IgG
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anti-Cytochrome C Oxidase Subunit I (COX1) (N-Term) antibody
COX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 318-599) antibodyCOX1 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 401-500) antibodyCOX1 适用: 小鼠, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 195-224) antibodyCOX1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB24524 unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (AA 474-513) antibodyCOX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (C-Term) antibodyCOX1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Subunit I (COX1) (C-Term) antibodyCOX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- COX1 (Cytochrome C Oxidase Subunit I (COX1))
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别名
- MT-CO1
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背景
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Background: Cytochrome c oxidase subunit I (CO1 or MTCO1) is 1 of 3 mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV. Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation. It is composed of 13 polypeptides. Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded. The cytochrome c oxidase family of enzymes have 4 redox centers, 2 hemes and 2 copper centers. In mitochondrial Complex IV, the 2 hemes are a and a3 and the 2 coppers are CuA and CuB. The 2 hemes and CuB are bound to subunit I. Acin-Perez et al. (2003) identified a cell line containing single and double missense mutations in the cytochrome c oxidase (COX) subunit I gene of mouse mitochondrial DNA. And they hypothesized that deleterious mutations can arise and become predominant, cultured cells can maintain several mtDNA haplotypes at stable frequencies, the respiratory chain has little spare COX capacity, and that the size of a cavity in the vicinity of val421 in MTCO1I of animal COX may affect the function of the enzyme.
Gene Full Name: cytochrome c oxidase subunit I
Sequence Similarities: Belongs to the SNAP-25 family.
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基因ID
- 4512
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UniProt
- P00395
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途径
- Proton Transport
抗原
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