Cyclin A 抗体 (AA 10-168) (Biotin)
Our Local Distributor
北京 101111
Quick Overview for Cyclin A 抗体 (AA 10-168) (Biotin) (ABIN7982110)
抗原
See all Cyclin A (CCNA2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-168
-
原理
- Anti-Cyclin A2/CCNA2 Antibody Biotin Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
预测反应
- Human Cyclin A2 shares 74.5% amino acid (aa) sequence identity with mouse Cyclin A2.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Cyclin A2 recombinant protein (Position: A10-K168). Human Cyclin A2 shares 74.5% amino acid (aa) sequence identity with mouse Cyclin A2.
-
亚型
- IgG
-
-
anti-Cyclin A2 (CCNA2) antibody
KO Validated CCNA2 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 105-233) antibodyCCNA2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6B4D11 unconjugated
anti-Cyclin A2 (CCNA2) antibodyKD Validated CCNA2 适用: 人 WB, FACS, ICC, IF (p) 宿主: 兔 Monoclonal 23GB1875 unconjugated Recombinant Antibody
anti-Cyclin A2 (CCNA2) (AA 10-168) antibodyCCNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 190-270) antibodyCCNA2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 51-84), (N-Term) antibodyCCNA2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14617 unconjugated
anti-Cyclin A2 (CCNA2) (AA 375-431) antibodyCCNA2 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (C-Term) antibodyCCNA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR369N unconjugated Recombinant Antibody
anti-Cyclin A2 (CCNA2) (C-Term) antibodyCCNA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Monoclonal BLR369N unconjugated Recombinant Antibody
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
-
别名
- CCNA2
-
背景
-
Background: Cyclin A2, known as CCNA2, is mapped to 4q27. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. And Cyclin A2 is synthesized at the onset of S phase and localizes to the nucleus, where the cyclin A2-CDK2 complex is implicated in the initiation and progression of DNA synthesis. Phosphorylation of CDC6 and MCM4 by the cyclin A2-CDK2 complex prevents re-replication of DNA during the cell cycle.
Gene Full Name: cyclin A2
Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.
-
基因ID
- 890
-
UniProt
- P20248
-
途径
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
-
