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LAG3 抗体 (AA 210-260) (PE)

Cited in 1 publication. This PE-conjugated 兔 多克隆 anti-LAG3 antibody specifically detects LAG3 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN748518
发货至: 中国
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Quick Overview for LAG3 抗体 (AA 210-260) (PE) (ABIN748518)

抗原

See all LAG3 抗体
LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

适用

  • 137
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人, 小鼠, 大鼠

宿主

  • 65
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  • 25
  • 7
  • 4
  • 1
  • 1

克隆类型

  • 95
  • 52
  • 2
多克隆

标记

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This LAG3 antibody is conjugated to PE

应用范围

  • 72
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  • 24
  • 15
  • 13
  • 13
  • 11
  • 9
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Western Blotting (WB)
  • 抗原表位

    • 15
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    • 3
    • 3
    • 3
    • 2
    • 1
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    AA 210-260

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3

    亚型

    IgG
  • 应用备注

    FCM(1:20-100)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Parodi, Battaglia, Kalli, Ferrera, Conteduca, Tardito, Stringara, Ivaldi, Negrini, Borgonovo, Simonato, Traverso, Carmignani, Fenoglio, Filaci: "CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." in: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).

  • 抗原

    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

    别名

    Lymphocyte Activation Gene 3

    背景

    Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3

    Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.

    基因ID

    297596

    UniProt

    Q5BK54

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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