Complement Factor I 抗体 (AA 19-220) (Biotin)
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Quick Overview for Complement Factor I 抗体 (AA 19-220) (Biotin) (ABIN7981569)
抗原
See all Complement Factor I (CFI) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-220
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原理
- Anti-Factor I/CFI Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- coli-derived human Factor I recombinant protein (Position: K19-D220). Human Factor I shares 70.7%,71.2% amino acid (aa) sequence identity with mouse,rat Factor I,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Factor I recombinant protein (Position: K19-D220). Human Factor I shares 70.7% and 71.2% amino acid (aa) sequence identity with mouse and rat Factor I, respectively.
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亚型
- IgG
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anti-Complement Factor I (CFI) (AA 358-603) antibody
CFI 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 28-243) antibodyCFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) (Internal Region) antibodyCFI 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 239-316) antibodyCFI 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-220) antibodyCFI 适用: 人, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 340-583) antibodyCFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Complement Factor I (CFI)
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别名
- CFI
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背景
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Background: Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene.
Gene Full Name: complement factor I
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基因ID
- 3426
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UniProt
- P05156
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途径
- Complement System
抗原
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