Girdin 抗体 (AA 1231-1836) (Biotin)
Our Local Distributor
北京 101111
Quick Overview for Girdin 抗体 (AA 1231-1836) (Biotin) (ABIN7980929)
抗原
See all Girdin (CCDC88A) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1231-1836
-
原理
- Anti-CCDC88A Antibody Biotin Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human CCDC88A recombinant protein (Position: K1231-D1836).
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
-
别名
- CCDC88A
-
背景
-
Background: Girdin is a protein that in humans is encoded by the CCDC88A gene. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Full Name: coiled-coil and HOOK domain protein 88A
-
基因ID
- 55704
-
UniProt
- Q3V6T2
抗原
-