CMA1 抗体 (AA 22-247) (Fluoro488)
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Quick Overview for CMA1 抗体 (AA 22-247) (Fluoro488) (ABIN7980183)
抗原
See all CMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-247
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原理
- Anti-Mast Cell Chymase/CMA1 Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human CMA1 shares 75%,74% amino acid (aa) sequences identity with mouse,rat CMA1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CMA1 recombinant protein (Position: I22-N247). Human CMA1 shares 75% and 74% amino acid (aa) sequences identity with mouse and rat CMA1, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CMA1 (Chymase 1, Mast Cell (CMA1))
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别名
- CMA1
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背景
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Background: Chymase is a major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. Chymase is mapped to 14q12. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II.
Gene Full Name: chymase 1
Sequence Similarities: Belongs to the peptidase S1 family. Granzyme subfamily.
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基因ID
- 1215
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UniProt
- P23946
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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