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CMA1 抗体 (AA 22-247) (Biotin)

The 兔 多克隆 anti-CMA1 antibody is suitable to detect CMA1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7980181
发货至: 中国
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Quick Overview for CMA1 抗体 (AA 22-247) (Biotin) (ABIN7980181)

抗原

See all CMA1 抗体
CMA1 (Chymase 1, Mast Cell (CMA1))

适用

  • 55
  • 34
  • 20
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 64
  • 8
  • 1
  • 1

克隆类型

  • 48
  • 26
多克隆

标记

  • 31
  • 10
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CMA1 antibody is conjugated to Biotin

应用范围

  • 42
  • 29
  • 21
  • 9
  • 9
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 18
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 22-247

    原理

    Anti-Mast Cell Chymase/CMA1 Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human CMA1 shares 75%,74% amino acid (aa) sequences identity with mouse,rat CMA1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CMA1 recombinant protein (Position: I22-N247). Human CMA1 shares 75% and 74% amino acid (aa) sequences identity with mouse and rat CMA1, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CMA1 (Chymase 1, Mast Cell (CMA1))

    别名

    CMA1

    背景

    Background: Chymase is a major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. Chymase is mapped to 14q12. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II.

    Gene Full Name: chymase 1

    Sequence Similarities: Belongs to the peptidase S1 family. Granzyme subfamily.

    基因ID

    1215

    UniProt

    P23946

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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