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C10orf2 抗体 (AA 39-635) (Biotin)

The 兔 多克隆 anti-C10orf2 antibody is suitable to detect C10orf2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN7979971
发货至: 中国
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Quick Overview for C10orf2 抗体 (AA 39-635) (Biotin) (ABIN7979971)

抗原

See all C10orf2 (C10ORF2) 抗体
C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

适用

  • 56
  • 29
  • 26
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 2

克隆类型

  • 55
  • 2
多克隆

标记

  • 26
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
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This C10orf2 antibody is conjugated to Biotin

应用范围

  • 31
  • 21
  • 17
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 12
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-635

    原理

    Anti-Twinkle/TWNK Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Twinkle,TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle,TWNK.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Twinkle/TWNK recombinant protein (Position: R39-K635). Human Twinkle/TWNK shares 87.8% amino acid (aa) sequence identity with mouse Twinkle/TWNK.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

    别名

    TWNK

    背景

    Background: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    Gene Full Name: twinkle mtDNA helicase

    基因ID

    56652

    UniProt

    Q96RR1
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