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CD40 Ligand 抗体 (AA 107-260) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-CD40 Ligand antibody (ABIN7976903) specifically detects CD40 Ligand in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7976903
发货至: 中国
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Quick Overview for CD40 Ligand 抗体 (AA 107-260) (Fluoro550) (ABIN7976903)

抗原

See all CD40 Ligand (CD40LG) 抗体
CD40 Ligand (CD40LG)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD40 Ligand antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 107-260

    原理

    Anti-CD40L/Cd40lg Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse CD40L recombinant protein (Position: E107-L260).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CD40 Ligand (CD40LG)

    别名

    Cd40lg

    背景

    Background: CD40 ligand (CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble CD40L may be involved in the process of restenosis and that it exerts its effect by triggering a complex group of inflammatory reactions on endothelial and mononuclear cells.CD40L plays a central role in the pathophysiology of acute coronary syndromes, and has a role in the pathogenesis of coronary artery lesions.

    Gene Full Name: CD40 ligand

    基因ID

    21947

    UniProt

    P27548

    途径

    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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