CD27 抗体 (AA 24-187) (Fluoro488)
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北京 101111
Quick Overview for CD27 抗体 (AA 24-187) (Fluoro488) (ABIN7976583)
抗原
See all CD27 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-187
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原理
- Anti-Cd27 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Cd27 recombinant protein (Position: P24-F187).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- CD27 (CD27 Molecule (CD27))
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别名
- Cd27
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背景
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Background: CD27 is a member of the tumor necrosis factor receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. And this receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Gene Full Name: CD27 antigen
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基因ID
- 21940
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UniProt
- P41272
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途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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