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Caspase 12 抗体 (N-Term)

The 兔 多克隆 anti-Caspase 12 antibody (ABIN7975205) specifically detects Caspase 12 in WB 和 IHC. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN7975205
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Caspase 12 抗体 (N-Term) (ABIN7975205)

抗原

See all Caspase 12 (CASP12) 抗体
Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

适用

  • 64
  • 58
  • 42
人, 大鼠

宿主

  • 98
  • 2

克隆类型

  • 98
  • 2
多克隆

标记

  • 41
  • 8
  • 6
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Caspase 12 antibody is un-conjugated

应用范围

  • 78
  • 40
  • 34
  • 28
  • 26
  • 26
  • 20
  • 19
  • 9
  • 6
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 16
    • 15
    • 14
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-Caspase-12/CASP12 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Caspase-12/CASP12 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-12.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

    别名

    CASP12

    背景

    Background: Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. The CASP12 gene was mapped to chromosome 11q22.3. Csp12L attenuates the inflammatory and innate immune response to endotoxins and in doing so may constitute a risk factor for developing sepsis. The estrogen-mediated inhibition of CSP12L expression is a built-in mechanism that has evolved to protect females from infection by favoring a more robust inflammatory response to pathogens, perhaps notably in childbirth.

    Gene Full Name: caspase 12 (gene/pseudogene)

    Sequence Similarities: Belongs to the peptidase C14A family.

    分子量

    39 kDa

    基因ID

    100506742

    UniProt

    Q6UXS9

    途径

    Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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