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Caspase 12 抗体 (AA 1-100)

CASP12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6137956
发货至: 中国
  • 抗原 See all Caspase 12 (CASP12) 抗体
    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
    抗原表位
    • 16
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 62
    • 53
    • 33
    宿主
    • 88
    • 3
    • 1
    克隆类型
    • 89
    • 3
    多克隆
    标记
    • 39
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Caspase 12 antibody is un-conjugated
    应用范围
    • 78
    • 40
    • 29
    • 27
    • 26
    • 26
    • 21
    • 18
    • 10
    • 6
    • 5
    • 5
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    MADEKPSNGV LVHMVKLLIK TFLDGIFDDL MENNVLNTDE IHLIGKCLKF VVSNAENLVD DITETAQIAG KIFREHLWNS KKQLSSDISS DGEREANMPG
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Caspase-12 (NP_001177945.2).
    亚型
    IgG
    Top Product
    Discover our top product CASP12 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
    别名
    CASP12 (CASP12 产品)
    别名
    Caspase-12 antibody, CASP-12 antibody, CASP12P1 antibody, caspase 12 antibody, caspase 12 (gene/pseudogene) antibody, Casp12 antibody, CASP12 antibody
    背景
    Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011],CASP12,CASP-12,CASP12P1,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Caspases,Ubiquitin,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CASP12
    分子量
    19 kDa/29 kDa/38 kDa
    基因ID
    100506742
    UniProt
    Q6UXS9
    途径
    Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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