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Caspase 12 抗体 (N-Term) (PE)

This 兔 多克隆 antibody specifically detects Caspase 12 in FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7975203
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Caspase 12 抗体 (N-Term) (PE) (ABIN7975203)

抗原

See all Caspase 12 (CASP12) 抗体
Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

适用

  • 64
  • 58
  • 42
人, 大鼠

宿主

  • 98
  • 2

克隆类型

  • 98
  • 2
多克隆

标记

  • 42
  • 8
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Caspase 12 antibody is conjugated to PE

应用范围

  • 79
  • 40
  • 33
  • 29
  • 26
  • 26
  • 20
  • 19
  • 9
  • 6
  • 5
  • 4
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 15
    • 14
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-Caspase-12/CASP12 Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-12.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

    别名

    CASP12

    背景

    Background: Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. The CASP12 gene was mapped to chromosome 11q22.3. Csp12L attenuates the inflammatory and innate immune response to endotoxins and in doing so may constitute a risk factor for developing sepsis. The estrogen-mediated inhibition of CSP12L expression is a built-in mechanism that has evolved to protect females from infection by favoring a more robust inflammatory response to pathogens, perhaps notably in childbirth.

    Gene Full Name: caspase 12 (gene/pseudogene)

    Sequence Similarities: Belongs to the peptidase C14A family.

    基因ID

    100506742

    UniProt

    Q6UXS9

    途径

    Apoptosis, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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