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MERTK 抗体 (N-Term) (Fluoro594)

The 兔 多克隆 anti-MERTK antibody is suitable to detect MERTK in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for FACS.
产品编号 ABIN7973602
发货至: 中国
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Quick Overview for MERTK 抗体 (N-Term) (Fluoro594) (ABIN7973602)

抗原

See all MERTK 抗体
MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

适用

  • 150
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  • 1
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人, 小鼠, 大鼠, 猴

宿主

  • 117
  • 38
  • 4
  • 3
  • 2

克隆类型

  • 88
  • 76
多克隆

标记

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This MERTK antibody is conjugated to Fluoro594

应用范围

  • 86
  • 72
  • 57
  • 38
  • 21
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  • 17
  • 13
  • 9
  • 9
  • 1
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 22
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    • 13
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    • 9
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    • 4
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    • 3
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term

    原理

    Anti-Tyrosine-protein kinase Mer MERTK Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human MERTK, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

    别名

    MERTK

    背景

    Background: Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. This gene is also very important in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

    Gene Full Name: MER proto-oncogene, tyrosine kinase

    Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.

    基因ID

    10461

    UniProt

    Q12866

    途径

    RTK signaling
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