MERTK 抗体 (AA 21-489) (Cy3)
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北京 101111
Quick Overview for MERTK 抗体 (AA 21-489) (Cy3) (ABIN7973588)
抗原
See all MERTK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-489
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原理
- Anti-MERTK Antibody Cy3 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MERTK recombinant protein (Position: A21-A489).
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
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别名
- MERTK
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背景
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Background: Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. This gene is also very important in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
Gene Full Name: MER proto-oncogene, tyrosine kinase
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基因ID
- 10461
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UniProt
- Q12866
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途径
- RTK signaling
抗原
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