BNIP3 抗体 (C-Term) (Fluoro647)
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Quick Overview for BNIP3 抗体 (C-Term) (Fluoro647) (ABIN7972529)
抗原
See all BNIP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-BNIP3 Antibody Fluoro647 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- identical to the related mouse,rat sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human BNIP3, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 50-155) antibody
BNIP3 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6A5F7 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 50-155) antibodyBNIP3 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E11F4 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 1-164) antibodyBNIP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 3-134) antibodyBNIP3 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 215-252) antibodyBNIP3 适用: 人, 小鼠 IF, IHC (p) 宿主: 兔 Polyclonal RB3385 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 152-187) antibodyBNIP3 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 112-124) antibodyBNIP3 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) (AA 1-164) antibodyBNIP3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) antibodyKO Validated BNIP3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4120 unconjugated Recombinant Antibody
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3) antibodyKD Validated BNIP3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB13585 unconjugated Recombinant Antibody
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
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别名
- BNIP3
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背景
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Background: The Bcl-2 nineteen kilodalton interacting protein 3 (BNIP3 or NIP3), is a hypoxia-inducible proapoptotic member of the Bcl-2 family that induces cell death by associating with the mitochondria. BNIP3, expressed in skeletal muscle and in the brain at low levels, is primarily localized to the nucleus of glial cells of the normal human brain, as well as in the malignant glioma cell line U251. BNIP3 expression in the cytoplasm increases and localizes with the mitochondria, contributing to induction of cell death. Cellular protein BNIP3 interacts with E1B-19K, BCL-2, BCL-xL, and EBV-BHRF1. BNIP3 contains Bcl-2 homology 3 (BH3) domain and COOH-terminal transmembrane (TM) domain. The BH3 domain of BNIP3 mediates Bcl-2/Bcl-X (L) heterodimerization and confers pro-apoptotic activity, whereas the TM domain is critical for homodimerization, pro-apoptotic function, and mitochondrial targeting.
Gene Full Name: BCL2 interacting protein 3
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基因ID
- 664
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UniProt
- Q12983
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途径
- Autophagy, Brown Fat Cell Differentiation
抗原
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