BIM 抗体 (AA 18-186)
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北京 101111
Quick Overview for BIM 抗体 (AA 18-186) (ABIN7972474)
抗原
See all BIM (BCL2L11) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 18-186
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原理
- Anti-Bim/Bcl2l11 Antibody
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Mouse Bcl2l11 shares 86.7%,98.8% amino acid (aa) sequence identity with human,rat Bcl2l11,respectively.
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产品特性
- Anti-Bim/Bcl2l11 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Bim/Bcl2l11 recombinant protein (Position: Q18-R186). Mouse Bcl2l11 shares 86.7% and 98.8% amino acid (aa) sequence identity with human and rat Bcl2l11, respectively.
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亚型
- IgG
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anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 2-120) antibody
BCL2L11 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 134-160) antibodyBCL2L11 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22105 unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer87) antibodyBCL2L11 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (C-Term) antibodyBCL2L11 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 130-165) antibodyBCL2L11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00963 unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 1-198) antibodyBCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibodyKO Validated BCL2L11 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB610 unconjugated Recombinant Antibody
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 51-150) antibodyBCL2L11 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer69) antibodyBCL2L11 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (pSer77) antibodyBCL2L11 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Mouse Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Mouse ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
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别名
- Bcl2l11
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背景
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Background: Bcl-2-like protein 11, commonly called BIM (Bcl-2?Interacting?Mediator of cell death), is a?protein?that in humans is encoded by the?BCL2L11?gene. BCL2 is a prototypic mammalian regulator of cell death. Certain members of the BCL2 family inhibit apoptosis, while other members facilitate this physiologic process of cell death. By screening a cDNA expression library using recombinant BCL2 as bait, O'Connor et al. isolated a small novel protein, which they referred to as BIM, with a 9-amino acid BH3 motif shared by most BCL2 homologs. BIM provokes apoptosis, and the BH3 region is required for BCL2 binding and for most of its cytotoxicity.
Gene Full Name: BCL2 like 11
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分子量
- 22 kDa
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基因ID
- 12125
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UniProt
- O54918
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途径
- PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
抗原
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