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BIM 抗体 (C-Term) (Cy3)

The Cy3-conjugated 兔 多克隆 anti-BIM antibody (ABIN7972454) specifically detects BIM in FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7972454
发货至: 中国
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Quick Overview for BIM 抗体 (C-Term) (Cy3) (ABIN7972454)

抗原

See all BIM (BCL2L11) 抗体
BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

适用

  • 140
  • 101
  • 68
  • 6
  • 3
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  • 1
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  • 1
人, 小鼠

宿主

  • 144
  • 7
  • 3
  • 1

克隆类型

  • 119
  • 36
多克隆

标记

  • 75
  • 12
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  • 2
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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  • 1
This BIM antibody is conjugated to Cy3

应用范围

  • 102
  • 61
  • 56
  • 46
  • 30
  • 21
  • 21
  • 20
  • 14
  • 13
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 14
    • 13
    • 12
    • 8
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    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Bim/BCL2L11 Antibody Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Bim/BCL2L11, which shares 80% amino acid (aa) sequence identity with mouse and rat BCL2L11.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

    别名

    BCL2L11

    背景

    Background: Bcl-2-like protein 11, commonly called BIM, is a protein that in humans is encoded by the BCL2L11 gene. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

    Gene Full Name: BCL2 like 11

    基因ID

    10018

    UniProt

    O43521

    途径

    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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