Survivin 抗体 (AA 1-142)
Our Local Distributor
北京 101111
Quick Overview for Survivin 抗体 (AA 1-142) (ABIN7972043)
抗原
See all Survivin (BIRC5) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 1-142
-
原理
- Anti-survivin/BIRC5 Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-survivin/BIRC5 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human Survivin recombinant protein (Position: M1-D142).
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
-
别名
- BIRC5
-
背景
-
Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin gene contains 4 exons. The survivin gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.
Gene Full Name: baculoviral IAP repeat containing 5
Sequence Similarities: Belongs to the IAP family.
-
分子量
- 16 kDa
-
基因ID
- 332
-
UniProt
- O15392
-
途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原
-