Survivin 抗体 (AA 1-142) (HRP)
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Quick Overview for Survivin 抗体 (AA 1-142) (HRP) (ABIN7972028)
抗原
See all Survivin (BIRC5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-142
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原理
- Anti-Survivin/BIRC5 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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预测反应
- coli-derived human Survivin recombinant protein (Position: M1-D142). Human Survivin shares 84.3%,83% amino acid (aa) sequence identity with mouse,rat Survivin,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Survivin recombinant protein (Position: M1-D142). Human Survivin shares 84.3% and 83% amino acid (aa) sequence identity with mouse and rat Survivin, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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别名
- BIRC5
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背景
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Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that in humans encoded by the BIRC5 gene. It is a member of the inhibitor of apoptosis (IAP) family. The survivin gene contains 4 exons. This gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions as inhibitor caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. And this protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.
Gene Full Name: baculoviral IAP repeat containing 5
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基因ID
- 332
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UniProt
- O15392
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途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原
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