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Survivin 抗体 (AA 1-140) (Fluoro550)

This 兔 多克隆 antibody specifically detects Survivin in FACS. It exhibits reactivity toward 小鼠.
产品编号 ABIN7972014
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Survivin 抗体 (AA 1-140) (Fluoro550) (ABIN7972014)

抗原

See all Survivin (BIRC5) 抗体
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

适用

  • 210
  • 94
  • 72
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 184
  • 55
  • 1
  • 1

克隆类型

  • 139
  • 102
多克隆

标记

  • 117
  • 18
  • 14
  • 8
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This Survivin antibody is conjugated to Fluoro550

应用范围

  • 173
  • 80
  • 67
  • 64
  • 61
  • 33
  • 33
  • 28
  • 26
  • 13
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 58
    • 19
    • 17
    • 16
    • 9
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-140

    原理

    Anti-Survivin/BIRC5 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Mouse Survivin shares 85%,91% amino acid (aa) sequence identity with human,rat Survivin,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Survivin recombinant protein (Position: M1-A140). Mouse Survivin shares 85% and 91% amino acid (aa) sequence identity with human and rat Survivin, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    别名

    BIRC5

    背景

    Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that in humans encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin gene contains 4 exons. This gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions as inhibitor caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells.

    Gene Full Name: baculoviral IAP repeat-containing 5

    Sequence Similarities: Belongs to the IAP family.

    基因ID

    11799

    UniProt

    O70201

    途径

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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