BIRC3 抗体 (AA 1-191) (Fluoro594)
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Quick Overview for BIRC3 抗体 (AA 1-191) (Fluoro594) (ABIN7972004)
抗原
See all BIRC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-191
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原理
- Anti-cIAP2/BIRC3 Antibody Fluoro594 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human cIAP2 recombinant protein (Position: M1-K191). Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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别名
- BIRC3
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背景
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Background: Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Gene Full Name: baculoviral IAP repeat containing 3
Sequence Similarities: Belongs to the IAP family.
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基因ID
- 330
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UniProt
- Q13489
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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