PAK4 抗体 (AA 501-591) (HRP)
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北京 101111
Quick Overview for PAK4 抗体 (AA 501-591) (HRP) (ABIN747527)
抗原
See all PAK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-591
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预测反应
- Human,Mouse,Rat,Dog,Cow,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PAK4
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亚型
- IgG
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anti-P21-Activated Kinase 4 (PAK4) (AA 299-542) antibody
PAK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 1-426) antibodyPAK4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 187-216) antibodyPAK4 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 120-280) antibodyPAK4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (pSer474), (pSer560), (pSer602) antibodyPAK4 适用: 人 WB, ELISA, IF 宿主: 兔 Monoclonal 2D1 unconjugated Recombinant Antibody
anti-P21-Activated Kinase 4 (PAK4) (AA 187-216) antibodyPAK4 适用: 人, 小鼠 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 23-72) antibodyPAK4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 156-187) antibodyPAK4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (AA 187-216) antibodyPAK4 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 4 (PAK4) (pSer474) antibodyPAK4 适用: 人, 小鼠, 大鼠, Cow WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA 1:500-1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Gentamicin sulfate
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注意事项
- This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PAK4 (P21-Activated Kinase 4 (PAK4))
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别名
- PAK4
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背景
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Synonyms: p21 activated kinase 4, p21CDKN1A activated kinase 4, PAK 4, Protein kinase related to S.cerevisiae STE20 effector for Cdc42Hs, Serine threonine kinase PAK 4, Serine/threonine protein kinase PAK 4, Serine/threonine protein kinase PAK4, KIAA1142, PAK4_HUMAN.
Background: p21-activated kinases (PAKs) belong to the family of serine/threonine kinases involved in the control of various cellular processes, including the cell cycle, dynamics of the cytoskeleton, apoptosis, oncogenic transformation, and transcription. All PAK family members are characterized by the presence of p21-binding domain. p21-activated kinases are regulated by the small GTP-binding proteins Rac and Cdc42, and lipids, which stimulate autophosphorylation and phosphorylation of exogenous substrates. Serine (Ser-474) is the likely autophosphorylation site in the kinase domain of PAK4 in vivo. Phosphospecific directed against serine 474 detect activated PAK4 on the Golgi membrane when PAK4 is co-expressed with activated Cdc42. Current data strongly implicates PAK-4 in oncogenesis. PAK4 is frequently overexpressed in human tumor cell lines of various tissue origins.
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基因ID
- 10298
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途径
- RTK signaling
抗原
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