BCL3 抗体 (AA 118-307) (HRP)
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Quick Overview for BCL3 抗体 (AA 118-307) (HRP) (ABIN7971885)
抗原
See all BCL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 118-307
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原理
- Anti-BCL3 Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human BCL3 recombinant protein (Position: E118-Y307).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
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别名
- BCL3
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背景
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Background: B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
Gene Full Name: BCL3 transcription coactivator
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基因ID
- 602
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UniProt
- P20749
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途径
- NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
抗原
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