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Angiotensin I Converting Enzyme 1 抗体 (N-Term) (Biotin)

The Biotin-conjugated 兔 多克隆 anti-Angiotensin I Converting Enzyme 1 antibody (ABIN7968663) specifically detects Angiotensin I Converting Enzyme 1 in WB, IHC 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7968663
发货至: 中国
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Quick Overview for Angiotensin I Converting Enzyme 1 抗体 (N-Term) (Biotin) (ABIN7968663)

抗原

See all Angiotensin I Converting Enzyme 1 (ACE) 抗体
Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

适用

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人, 小鼠

宿主

  • 167
  • 59
  • 3
  • 1

克隆类型

  • 146
  • 84
多克隆

标记

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This Angiotensin I Converting Enzyme 1 antibody is conjugated to Biotin

应用范围

  • 131
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  • 17
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  • 12
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 16
    • 16
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    • 15
    • 13
    • 12
    • 12
    • 5
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    N-Term

    原理

    Anti-Angiotensin Converting Enzyme 1/ACE Antibody Biotin Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by two amino acids,and from the related rat sequence by four amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Angiotensin Converting Enzyme 1, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

    别名

    ACE

    背景

    Background: Angiotensin I converting enzyme (ACE), also called DCP or CD143 is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. This gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.

    Gene Full Name: angiotensin I converting enzyme

    Sequence Similarities: Belongs to the peptidase M2 family.

    基因ID

    1636

    UniProt

    P12821

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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