Angiotensin I Converting Enzyme 1 抗体 (AA 651-864)
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Quick Overview for Angiotensin I Converting Enzyme 1 抗体 (AA 651-864) (ABIN7968629)
抗原
See all Angiotensin I Converting Enzyme 1 (ACE) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 651-864
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原理
- Anti-Angiotensin Converting Enzyme 1/ACE Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human ACE shares 73%,76% amino acid (aa) sequences identity with mouse,rat ACE,respectively.
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产品特性
- Anti-Angiotensin Converting Enzyme 1/ACE Antibody. Tested in IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ACE recombinant protein (Position: K651-Y864). Human ACE shares 73% and 76% amino acid (aa) sequences identity with mouse and rat ACE, respectively.
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亚型
- IgG
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anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 1160-1306) antibody
ACE 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 651-864) antibodyACE 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IHC (fro), IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 814-1071) antibodyACE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 801-900) antibodyACE 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (Middle Region) antibodyACE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 592-701) antibodyACE 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 592-701) antibodyACE 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6A4 unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) antibodyACE 适用: 人 ELISA 宿主: 小鼠 Monoclonal 9B9 unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 30-182) antibodyACE 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3H7E4 unconjugated
anti-Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE) (AA 30-270) antibodyACE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, -Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, RatWestern blot, 0.1-0.5 μg/mL, Human, MouseImmunocytochemistry/Immunofluorescence, 2 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
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别名
- ACE
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背景
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Background: Angiotensin-converting enzyme (ACE), an exopeptidase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), which mediates extracellular volume (i.e. that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II. Using a DNA marker at the growth hormone gene locus, which they characterized as 'extremely polymorphic' and which showed no recombination with ACE, ACE was mapped to 17q22-q24, consistent with the in situ hybridization mapping to 17q23. ACE, or kininase II, is a dipeptidyl carboxypeptidase that plays an important role in blood pressure regulation and electrolyte balance by hydrolyzing angiotensin I into angiotensin II, a potent vasopressor, and aldosterone-stimulating peptide. The enzyme is also able to inactivate bradykinin, a potent vasodilator.
Gene Full Name: angiotensin I converting enzyme
Sequence Similarities: Belongs to the peptidase M2 family.
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分子量
- 180 kDa
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基因ID
- 1636
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UniProt
- P12821
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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