AGRN 抗体 (AA 1864-2068) (HRP)
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Quick Overview for AGRN 抗体 (AA 1864-2068) (HRP) (ABIN7967228)
抗原
See all AGRN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1864-2068
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原理
- Anti-Agrin/AGRN Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Agrin/AGRN recombinant protein (Position: S1864-P2068).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- AGRN (Agrin (AGRN))
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别名
- AGRN
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背景
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Background: Agrin is a protein that in humans is encoded by the AGRN gene. It is mapped to 1p36.33. This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: agrin
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基因ID
- 375790
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UniProt
- O00468
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途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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