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AGRN 抗体 (AA 1864-2068) (HRP)

The 兔 多克隆 anti-AGRN antibody is suitable to detect AGRN in samples from 人, 大鼠 和 小鼠. It has been validated for IHC, WB 和 ELISA.
产品编号 ABIN7967228
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for AGRN 抗体 (AA 1864-2068) (HRP) (ABIN7967228)

抗原

See all AGRN 抗体
AGRN (Agrin (AGRN))

适用

人, 大鼠, 小鼠

宿主

  • 34
  • 5

克隆类型

  • 34
  • 5
多克隆

标记

  • 20
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AGRN antibody is conjugated to HRP

应用范围

  • 18
  • 12
  • 12
  • 10
  • 9
  • 5
  • 5
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), ELISA
  • 抗原表位

    • 11
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1864-2068

    原理

    Anti-Agrin/AGRN Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Agrin/AGRN recombinant protein (Position: S1864-P2068).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    AGRN (Agrin (AGRN))

    别名

    AGRN

    背景

    Background: Agrin is a protein that in humans is encoded by the AGRN gene. It is mapped to 1p36.33. This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Gene Full Name: agrin

    基因ID

    375790

    UniProt

    O00468

    途径

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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