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Smad2/3 抗体 (AA 30-80) (Cy5.5)

This anti-Smad2/3 antibody is a 兔 多克隆 antibody detecting Smad2/3 in WB, FACS, IF (cc) 和 IF (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN747028
发货至: 中国

Quick Overview for Smad2/3 抗体 (AA 30-80) (Cy5.5) (ABIN747028)

抗原

Smad2/3 (SMAD2/3) (Smad2/3 Transcription Factor (SMAD2/3))

适用

  • 43
  • 31
  • 31
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 41
  • 2
  • 1

克隆类型

  • 44
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Smad2/3 antibody is conjugated to Cy5.5

应用范围

  • 33
  • 13
  • 12
  • 12
  • 10
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 11
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-80

    交叉反应

    人, 小鼠, Pig, 大鼠

    预测反应

    Cow,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Smad2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Smad2/3 (SMAD2/3) (Smad2/3 Transcription Factor (SMAD2/3))

    别名

    Smad2/3

    背景

    Synonyms: Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, SMAD 2, Smad2, hSMAD2, SMAD2, MADH2, MADR2, SMAD2_HUMAN.

    Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

    基因ID

    4087

    UniProt

    Q15796
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