CDK2 抗体 (pThr160)
Quick Overview for CDK2 抗体 (pThr160) (ABIN747008)
抗原
See all CDK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr160
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human CDK2 around the phosphorylation site of Thr160 [TY(p-T)HE]
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亚型
- IgG
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应用备注
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WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages." in: The EMBO journal, Vol. 36, Issue 5, pp. 604-616, (2017) (PubMed).
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A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages." in: The EMBO journal, Vol. 36, Issue 5, pp. 604-616, (2017) (PubMed).
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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别名
- Cdk2
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背景
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Synonyms: p-CDH2 Thr160, CDH2 Thr160, CDH2 T160,Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase, CDK2_HUMAN.
Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
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基因ID
- 1017
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途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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