ADAM10 抗体 (AA 214-325) (PE)
Our Local Distributor
北京 101111
Quick Overview for ADAM10 抗体 (AA 214-325) (PE) (ABIN7966218)
抗原
See all ADAM10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 214-325
-
原理
- Anti-ADAM10 Antibody PE Conjugated
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human ADAM10 recombinant protein (Position: T214-D325).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
-
别名
- ADAM10
-
背景
-
Background: ADAM10, A Disintegrin and Metalloproteinase Domain 10, is also known as AD10. ADAM10 is a member of the ADAM family and members of this family are cell surface proteins with a unique structure possessing both potential adhesion and protease function. The ADAM10 gene is mapped to chromosome 15q21.3-q23. ADAM proteins contain an N-terminal signal sequence, followed by a prodomain, a metalloprotease-like domain, a disintegrin-like domain, a cysteine-rich region, an EGF -like repeat, a transmembrane domain, and a C-terminal cytoplasmic tail. Conversion of the membrane-bound precursor to a secreted mature protein is mediated by a protease termed TNFA convertase. ADAM10 possesses TNFA convertase activity.
Gene Full Name: ADAM metallopeptidase domain 10
-
基因ID
- 102
-
UniProt
- O14672
-
途径
- Notch Signaling, EGFR Signaling Pathway
抗原
-