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beta Actin 抗体 (N-Term) (APC)

This 兔 多克隆 antibody specifically detects beta Actin in FACS. It exhibits reactivity toward 人, 小鼠, 大鼠, 小鸡, 猴 和 斑马鱼.
产品编号 ABIN7965700
发货至: 中国
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Quick Overview for beta Actin 抗体 (N-Term) (APC) (ABIN7965700)

抗原

See all beta Actin (ACTB) 抗体
beta Actin (ACTB) (Actin, beta (ACTB))

适用

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人, 小鼠, 大鼠, 小鸡, 猴, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This beta Actin antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    N-Term

    原理

    Anti-beta Actin/ACTB Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human beta Actin, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    beta Actin (ACTB) (Actin, beta (ACTB))

    别名

    ACTB

    背景

    Background: beta-Actin (ACTB) also known as BETA-ACTIN or ACTIN, CYTOPLASMIC, 1, is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Ueyama et al. (1996) used fluorescence in situ hybridization to map ACTB to 7p22. By PCR of somatic cell hybrid DNAs, they mapped 4 ACTB pseudogenes to other chromosomes. Karakozova et al. (2006) found that arginylation of beta-actin regulates cell motility. The majority of Ate1-null cells appeared smaller than wildtype cells and were apparently unable to form a lamella during movement along the substrate. Karakozova et al. (2006) concluded that arginylation of beta-actin apparently represents a critical step in the actin N-terminal processing needed for actin functioning in vivo.

    Gene Full Name: actin beta

    Sequence Similarities: Belongs to the actin family.

    基因ID

    60

    UniProt

    P60709

    途径

    Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
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