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14-3-3 zeta 抗体 (Middle Region) (Cy3)

The 兔 多克隆 anti-14-3-3 zeta antibody is suitable to detect 14-3-3 zeta in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7964747
发货至: 中国
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Room 801-803
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Quick Overview for 14-3-3 zeta 抗体 (Middle Region) (Cy3) (ABIN7964747)

抗原

See all 14-3-3 zeta (YWHAZ) 抗体
14-3-3 zeta (YWHAZ)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This 14-3-3 zeta antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    Middle Region

    原理

    Anti-14-3-3 zeta/delta/YWHAZ Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human 14-3-3 zeta/delta, which shares 97.8% amino acid (aa) sequence identity with both mouse and rat 14-3-3 zeta/delta.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    14-3-3 zeta (YWHAZ)

    别名

    YWHAZ

    背景

    Background: 14-3-3 protein zeta/delta (14-3-3ζ) is a protein that in humans is encoded by the YWHAZ gene on chromosome 8. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

    Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

    基因ID

    7534

    UniProt

    P63104

    途径

    Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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