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SYK 抗体 (pTyr323) (Cy7)

This Cy7-conjugated 兔 多克隆 anti-SYK antibody specifically detects SYK in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN746264
发货至: 中国
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Quick Overview for SYK 抗体 (pTyr323) (Cy7) (ABIN746264)

抗原

See all SYK 抗体
SYK (Spleen tyrosine Kinase (SYK))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SYK antibody is conjugated to Cy7

应用范围

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Western Blotting (WB)
  • 抗原表位

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    pTyr323

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr323

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    SYK (Spleen tyrosine Kinase (SYK))

    别名

    Syk

    背景

    Synonyms: syk Tyr323, Tyrosine-protein kinase SYK Spleen tyrosine kinase [Contains: 72 kDa tyrosine-protein kinase SYK, 40 kDa tyrosine-protein kinase SYK, KSYK_HUMAN.

    Background: Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk, Spleen tyrosine kinase, Tyrosine protein kinase SYK.

    基因ID

    6850

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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