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Serotonin Receptor 1A 抗体 (3rd Intracellular Loop)

The 兔 多克隆 anti-Serotonin Receptor 1A antibody (ABIN7885388) specifically detects Serotonin Receptor 1A in WB, IHC 和 IF. The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN7885388
发货至: 中国
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Quick Overview for Serotonin Receptor 1A 抗体 (3rd Intracellular Loop) (ABIN7885388)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体
Serotonin Receptor 1A (HTR1A)

适用

  • 49
  • 32
  • 31
  • 1
  • 1
大鼠, 小鼠

宿主

  • 43
  • 5
  • 2

克隆类型

  • 46
  • 4
多克隆

标记

  • 24
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Serotonin Receptor 1A antibody is un-conjugated

应用范围

  • 35
  • 18
  • 14
  • 13
  • 13
  • 9
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

质量等级

Carrier-free
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    3rd Intracellular Loop, AA 251-266

    原理

    A Rabbit Polyclonal Antibody to 5-Hydroxytryptamine Receptor 1A

    预测反应

    Mouse - identical

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine receptor 1A

    亚型

    IgG
  • 应用备注

    WB: 1:200

    FC: The optimal concentration should be determined by the user

    ICC: The optimal concentration should be determined by the user

    IHC: 1:100

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7236780)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    Serotonin Receptor 1A (HTR1A)

    别名

    5-Hydroxytryptamine receptor 1A

    背景

    Synonyms: 5-Hydroxytryptamine receptor 1A, Serotonin receptor 1A

    Description: Serotonin (5-hydroxytryptamine, 5-HT1) is an important neurotransmitter in the central nervous system (CNS) that exerts its neuronal activity via 5-HT receptors.5-HT receptors are subdivided into seven families termed 5-HT1 through 5-HT7.1 The 5-HT receptor families belong to the G-protein coupled receptor superfamily with the exception of 5-HT3 receptor class which belongs to the ligand-gated ion channels.2The 5-HT1 receptor class comprises of five different receptors (5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F) which share 41-63 % overall sequence identity and couple preferentially to Gi/Go to inhibit cAMP formation.2The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the CNS, 5-HT1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala and raphe nucelus in high densities, and was also demonstrated in a variety of tissues from various species.2,3 Activation of 5-HT1A receptor decreases blood pressure and heart rate, and is involved in learning, memory, relieving anxiety and depression.1,4

    基因ID

    24473

    UniProt

    P19327

    途径

    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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