YY1 抗体
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北京 101111
Quick Overview for YY1 抗体 (ABIN7882715)
抗原
See all YY1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- YY1 Antibody / Ying-Yang 1
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纯化方法
- Protein A/G affinity
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免疫原
- A His-tagged YY1 protein was used as the immunogen for the YY1 antibody.
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亚型
- IgG2, kappa
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应用备注
- Optimal dilution of the YY1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the YY1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- YY1 (YY1 Transcription Factor (YY1))
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别名
- YY1
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背景
- The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal end. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3' enhancer and immunoglobulin heavy-chain i 1/2E1 site as well as the P5 promoter of the adenoassociated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others.
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UniProt
- P25490
抗原
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