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YY1 抗体

The 小鼠 单克隆 anti-YY1 antibody is suitable to detect YY1 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7882714
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for YY1 抗体 (ABIN7882714)

抗原

See all YY1 抗体
YY1 (YY1 Transcription Factor (YY1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This YY1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

YY1-5436
  • 原理

    YY1 Antibody / Ying-Yang 1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A His-tagged YY1 protein was used as the immunogen for the YY1 antibody.

    亚型

    IgG2, kappa
  • 应用备注

    Optimal dilution of the YY1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the YY1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    YY1 (YY1 Transcription Factor (YY1))

    别名

    YY1

    背景

    The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal end. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3' enhancer and immunoglobulin heavy-chain i 1/2E1 site as well as the P5 promoter of the adenoassociated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others.

    UniProt

    P25490
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