RENT1/UPF1 抗体
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北京 101111
Quick Overview for RENT1/UPF1 抗体 (ABIN7882643)
抗原
See all RENT1/UPF1 (UPF1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RENT1 Antibody / hUPF1
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序列
- NMDSMPELQK LQQLKDETGE LSSADEKRYR ALKRT
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纯化方法
- Affinity purified
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免疫原
- Amino acids NMDSMPELQKLQQLKDETGELSSADEKRYRALKRT AE from the human protein were used as the immunogen for the RENT1 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the RENT1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RENT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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别名
- RENT1
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背景
- Regulator of nonsense transcripts 1 is a protein that in humans is encoded by the UPF1 gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. And this protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.
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UniProt
- Q92900
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途径
- SARS-CoV-2 Protein Interactome
抗原
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