Recombinant TFF1 抗体
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北京 101111
Quick Overview for Recombinant TFF1 抗体 (ABIN7882561)
抗原
See all TFF1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant pS2 Antibody / TFF1
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序列
- CFDDTVRGVP WCFYPNTIDV PPEEECEF
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纯化方法
- Protein A affinity chromatography
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免疫原
- Amino acids CFDDTVRGVPWCFYPNTIDVPPEEECEF were used as the immunogen for this recombinant pS2 antibody.
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亚型
- IgG, kappa
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anti-Trefoil Factor 1 (TFF1) antibody
TFF1 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal TFF1-2133 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 25-84), (pSer2) antibodyTFF1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) antibodyTFF1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-87) antibodyTFF1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-81) antibodyTFF1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 57-84) antibodyTFF1 适用: 人, Cynomolgus IHC 宿主: 小鼠 Monoclonal GE2-same as R47-94 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 IHC, WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-88) antibodyTFF1 适用: 人 IHC 宿主: 小鼠 Monoclonal 482M unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 22-87) antibodyTFF1 适用: 小鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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The optimal dilution of the recombinant pS2 antibody for each application should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant pS2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TFF1 (Trefoil Factor 1 (TFF1))
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别名
- pS2
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背景
- It recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. It is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
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UniProt
- P04155
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途径
- EGFR Signaling Pathway
抗原
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