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TFF1 抗体 (AA 22-87)

TFF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518960
发货至: 中国
  • 抗原 See all TFF1 抗体
    TFF1 (Trefoil Factor 1 (TFF1))
    抗原表位
    • 27
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-87
    适用
    • 80
    • 17
    • 16
    • 13
    • 8
    人, 小鼠, 大鼠
    宿主
    • 44
    • 43
    • 1
    克隆类型
    • 47
    • 41
    多克隆
    标记
    • 55
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TFF1 antibody is un-conjugated
    应用范围
    • 44
    • 34
    • 34
    • 29
    • 19
    • 12
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Trefoil factor 1(Tff1) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Trefoil factor 1(Tff1) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
    Gene Name: trefoil factor 1
    Protein Name: Trefoil factor 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived mouse Tff1 recombinant protein (Position: Q22-F87). Mouse Tff1 shares 67.2% and 83.6% amino acid (aa) sequence identity with human and rat Tff1, respectively.
    亚型
    IgG
    Top Product
    Discover our top product TFF1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ELISA: Concentration: 2-8 μg/mL, Tested Species: Mouse
    Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    TFF1 (Trefoil Factor 1 (TFF1))
    别名
    Tff1 (TFF1 产品)
    别名
    BCEI antibody, D21S21 antibody, HP1.A antibody, HPS2 antibody, pNR-2 antibody, pS2 antibody, Bcei antibody, PS2 antibody, bcei antibody, d21s21 antibody, hp1.a antibody, hps2 antibody, p1 antibody, p1-a antibody, pnr-2 antibody, ps2 antibody, tff1 antibody, xP1 antibody, xp1-L antibody, xp1 antibody, TFF1 antibody, Ps2 antibody, trefoil factor 1 antibody, trefoil factor 1 S homeolog antibody, trefoil factor 1, gene 2 S homeolog antibody, TFF1 antibody, Tff1 antibody, tff1.S antibody, tff1.2.S antibody, LOC100358238 antibody
    背景
    TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

    Synonyms: Trefoil factor 1, Protein pS2, Tff1, Bcei, Ps2
    基因ID
    21784
    UniProt
    Q08423
    途径
    EGFR Signaling Pathway
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