Stathmin 1 抗体
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北京 101111
Quick Overview for Stathmin 1 抗体 (ABIN7882370)
抗原
See all Stathmin 1 (STMN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Op18 Antibody / Stathmin 1 / STMN1
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human Stathmin 1 protein was used as the immunogen for the Op18 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Op18 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Op18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Stathmin 1 (STMN1)
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别名
- Op18
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背景
- Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
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UniProt
- P16949
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途径
- MAPK Pathway, Microtubule Dynamics
抗原
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