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Stathmin 1 抗体

The 小鼠 单克隆 anti-Stathmin 1 antibody is suitable to detect Stathmin 1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7882366
发货至: 中国
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Room 801-803
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Quick Overview for Stathmin 1 抗体 (ABIN7882366)

抗原

See all Stathmin 1 (STMN1) 抗体
Stathmin 1 (STMN1)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Stathmin 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

STMN1-8439
  • 原理

    Oncoprotein 18 Antibody / OP18 / Stathmin 1

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment of human Stathmin 1 protein was used as the immunogen for the Oncoprotein 18 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Oncoprotein 18 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Oncoprotein 18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Stathmin 1 (STMN1)

    别名

    Oncoprotein 18

    背景

    Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

    UniProt

    P16949

    途径

    MAPK Pathway, Microtubule Dynamics
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